From disease modelling to personalised therapy in patients with CEP290 mutations [version 1; referees: 2 approved]

Mutations that give rise AA Ni-Cd and Ni-Mh Batteries and Battery Packs to premature termination codons are a common cause of inherited genetic diseases.When transcripts containing these changes are generated, they are usually rapidly removed by the cell through the process of nonsense-mediated decay.Here we discuss observed changes in transcripts

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Shisha microbiota: the good, the bad and the not so ugly

Abstract Objective Over the last decade, there has been a rapid expansion of the trendy water pipe smoking around the world especially among younger adults.The initial objective of this study was to identify the microbiota of the shisha, which may either be of no harm for the smoker or enhance the threat on his well-being.The total DNA for the meta

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Estimation of the cost-effectiveness of HIV prevention portfolios for people who inject drugs in the United States: A model-based analysis.

BACKGROUND:The risks of HIV transmission associated with the opioid epidemic make cost-effective programs for people who inject drugs (PWID) a public health priority.Some of these programs have benefits beyond prevention of HIV-a critical consideration given that injection drug use is increasing across most United States demographic groups.To ident

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A Synthetic Signal Varied Weight Indicator in Bacteria

Biomolecular computing devices always work in a complex biochemical environment.The weight which shows the importance degree of a specific signal may vary in different environments because it may be influenced by other signals even in the absence of direct interaction.To measure a signal accurately, several biomolecular computing devices always nee

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